Degenerativna bolest aterioventrikularnih zalistaka u pasa primljenih na kliniku za unutarnje bolesti Veterinarskog fakulteta Sveučilišta u Zagrebu (2010.-2013.)

master's thesis

• Title (english): Chronic degenarative valve disease in dogs addmited at the Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb (2010-2013)
• Author: Ivana Pintar
• Mentor: Vesna Matijatko (mentor)
• Mentor: Marin Torti (komentor)
• Committee member: Iva Šmit
• Committee member: Marin Torti
• Committee member: Vesna Matijatko
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Internal Diseases Clinic); Zagreb
• Defense date and country: 2016-01-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Degenerativna bolest atrioventrikulskih zalistaka je najučestalija je bolest srca u pasa
(čini oko 75% svih bolesti srca), a promjenama su najčešće zahvaćeni mitralni zalisci. Bolest
pripada u skupinu stečenih bolesti srca, a degenerativni proces karakteriziran je
miksomatoznom proliferacijom i fibrozom rubova zalistaka i korda tendineja. Predstavlja
najčešći uzrok mitralne regurgitacija u pasa. Uznapredovali degenerativni procesi dovode do
pojave regurgitacije u području atrioventrikulskih zalistaka, a s vremenom kod nekih životinja
mogu dovesti do pojave zastojnog zatajenja srca.. Istraživanje je obuhvatilo 47 pasa primljenih
na Kliniku za unutarnje bolesti Veterinarskog fakulteta u Zagrebu, kojima je u postupku
dijagnostike dokazna degenerativna bolest zalistaka u razdoblju od 1. siječnja 2010. do 31.
prosinca 2013.
Na temelju rezultata ovog istraživanja došli smo do zaključka da postoji pasminska
predispozicija za razvoj bolesti, te da se bolest češće javlja u muških pasa, starije dobi i tjelesne
mase manje od 20 kilograma. Na temelju dijagnostičkih podataka potvrdili smo da se
progresijom bolesti povećava prevalencija i ozbiljnost kliničkih simptoma karakterističnih za
degenerativnu bolest atrioventrikularnih zalistaka.

Abstract (english)

Chronic degenerative valvular disease is the most common heart disease in dogs
(accounting for approximately 75% of canine heart disease cases) and most commonly affects
the mitral valve. The disease belongs to the group of acquired heart disease, characterized by a
myxomatous proliferation and fibrosis of valve leaflets and tendious chordae. It is most
common cause of mitral regurgitation in dogs. The progression of valve degeneration leads to
development of regurgitation in the atrioventricular valves, and in some animals, eventually to
congestive heart failure. The study included 47 dogs admitted at the Clinic for Internal Disease,
Faculty of Veterinary Medicine in Zagreb, between January 1 2010 to December 31 2013, that
were then diagnosed with chronic degenerative valvular disease.
Based on the results of this study, we concluded that there is a breed predisposition for
developing the disease, and that the disease is more common in male dogs, older dogs and small
breed dogs that weight less than 20 kilograms. Based on the diagnostic data, we confirmed that
the progression of the disease increases the prevalence and severity of clinical signs that are
characteristic for chronic degenerative valvular disease.

• Keywords: pas; degenerativna bolest atrioventrikularnih zalistaka; mitralna regurgitacija; dijagnoza.
• Keywords (english): dog; chronic degenrative valvular disease; mitral regurgitation; diagnosis
• Language: croatian
• URN:NBN: urn:nbn:hr:178:850716
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2016-01-18 11:11:00