Akutna upala gušterače u pasa

master's thesis

• Title (english): Acute Pancreatitis in Dogs
• Author: Marija-Katarina Pletikapić
• Mentor: Nada Kučer (mentor)
• Mentor: Iva Šmit (mentor)
• Committee member: Dalibor Potočnjak (predsjednik povjerenstva)
• Committee member: Vladimir Mrljak (član povjerenstva)
• Committee member: Nada Kučer (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Internal Diseases Clinic); Zagreb
• Defense date and country: 2017-02-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine

Abstract

Akutna upala gušterače je česta bolest pasa kod koje dolazi do autodigestije gušterače zbog aktivacije enzima gušterače. Točan uzrok bolesti se ne zna, ali postoje brojni čimbenici koji povećavaju rizik za razvoj bolesti, kao što su masna prehrana, pretilost, hiperlipidemija, prisutnost nekih bolesti (diabetes mellitus, hiperadrenokorticizam i dr.), lijekovi i dr. Mogu obolijeti različite pasmine pasa, neovisno o dobi i spolu. Međutim, zabilježena je češća pojava bolesti u pasa srednje i starije dobi te je u nekih pasmina pasa, pogotovo kod minijaturnih šnaucera, zabilježen povećani rizik za razvoj bolesti. Očituje se različitim, nespecifičnim kliničkim znakovima, a neki od najčešćih su povraćanje, bol u abdomenu, anoreksija i dehidracija. U ovom diplomskom radu obrađene su brojne dijagnostičke pretrage koje se koriste za postavljanje dijagnoze, počevši od detaljanog kliničkog pregleda do pretrage specifičnim imunoenzimnim testom – cPLI (canine pancreatic lipase immunoreactivity) koji ima najvišu osjetljivost i specifičnost od svih testova koji su danas dostupni za otkrivanje pankreatitisa kod pasa. Također, detaljno je obrađeno liječenje pankreatitisa koje se bazira na nadoknadi tekućine i uspostavljanju acido-bazne ravnoteže, sprječavanju povraćanja i ublažavanju bolova te na što bržem povratku na enteralnu prehranu.

Abstract (english)

Acute pancreatitis is very common disease in dogs in which come to autodigestion of pancreas because of the activation of pancreatic enzymes. The exact cause of canine pancreatitis is unknown, but there are many risk factors, such as fatty meals, obesity, hyperlipidemia, some diseases (diabetes mellitus, hyperadrenocorticism etc.), drugs etc. Dogs of any breed can develop pancreatits, independently of age and sex. However, most dogs with pancreatitis are middle-age or older and it have been reported that some breeds, especially Miniature Schnauzers, are at increased risk for developing pancreatitis. It is manifested with different, non-specific clinical signs and some of the most common are vomiting, abdominal pain, anorexia and dehydration. In this master thesis are described many of diagnostic metods that are using in diagnosing pancreatitis, from detailed clinical examination to specific immunotest – cPLI (canine pancreatic lipase immunoreactivity) which has the highest sensitivity and specificity of all tests that are today available for diagnosing pancreatitis. Also, there are described detailed therapy of pancreatits which is based on fluid therapy and establishing acid-base balance, preventing vomiting, pain management and early enteral nutrition.

• Keywords: Akutna upala gušterače
• Keywords (english): Acute pancreatic inflammation
• Language: croatian
• URN:NBN: urn:nbn:hr:178:837003
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-07-23 12:30:28