Tumori kože u preživača

master's thesis

• Title (croatian): Skin tumors in ruminants
• Author: Hana Paklar
• Mentor: Lidija Medven Zagradišnik (mentor)
• Committee member: Andrea Gudan Kurilj (predsjednik povjerenstva)
• Committee member: Ivan-Conrado Šoštarić-Zuckermann (član povjerenstva)
• Committee member: Lidija Medven Zagradišnik (član povjerenstva)
• Committee member: Branka Artuković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-04, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Tumori kože smatraju se najučestalijim tumorima, no tumori kože preživača općenito su
rijetko dijagnosticirani i opisani. Pojavnost tumora kože u preživača povezuje se s prekomjernim
izlaganjem ultraljubičastom (UV) zračenju i infektivnim agensima (virusi iz porodice
Papillomaviridae). Osim toga važnu ulogu ima i pigmentacija kože i dlake te gustoća dlačnog
pokrivača. Tumore kože dijelimo na benigne i maligne prema biološkom ponašanju, a glavna
podjela temelji se na porijeklu tumorskih stanica pa tako razlikujemo epitelne, melanocitne i
mezenhimalne tumore kože. Među ovim tumorima posebno se ističe planocelularni karcinom
(SCC). Opisan je u velikih i malih preživača, a bilježi ga pasminska predispozicija, lokalno
destruktivno širenje i niska metastatska sposobnost. Sekundarni tumori kože rijetki su u svih vrsta
domaćih životinja, a posebno su rijetki u preživača. Dijagnoza se postavlja na temelju
histopatološke pretrage i imunohistokemijske metode. Liječenje koje dolazi u obzir uglavnom je
samo kirurška ekscizija, dok će se prognoza temeljiti na više parametara.

Abstract (english)

Skin tumors are considered the most common tumors, but ruminant skin tumors are
generally rarely diagnosed and described. The occurrence of skin tumors in ruminants is associated
with excessive exposure to ultraviolet (UV) radiation and infectious agents (viruses from the
Papillomaviridae family). In addition, the pigmentation of the skin and hair and the density of hair
play an important role. Skin tumors are divided into benign and malignant according to their
biological behavior, and the main division is based on the origin of the tumor cells, thus
distinguishing between epithelial, melanocytic and mesenchymal skin tumors. Among these
tumors, squamous cell carcinoma (SCC) stands out. It is described in large and small ruminants,
and is noted for its breed predisposition, local destructive invasion and low metastatic ability.
Secondary skin tumors are rare in all species of domestic animals, and especially rare in ruminants.
The diagnosis is based on histopathological examination and immunohistochemical methods. The
treatment that comes into consideration is mostly only surgical excision and the prognosis will be
based on several parameters.

• Keywords: tumori kože; patološki aspekt; preživači
• Keywords (english): skin tumors; pathological aspect; ruminants
• Language: croatian
• URN:NBN: urn:nbn:hr:178:735093
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2024-05-08 09:29:36