Dijagnostika i terapija najčešćih bolesti jetre u pasa

master's thesis

• Title (english): Diagnosis and therapy of the most common liver diseases in dogs
• Author: Helena Torinek
• Mentor: Martina Crnogaj (mentor)
• Mentor: Nada Kučer (mentor)
• Committee member: Darko Grden (predsjednik povjerenstva)
• Committee member: Iva Šmit (član povjerenstva)
• Committee member: Martina Crnogaj (član povjerenstva)
• Committee member: Nada Kučer (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-09, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Jetra je najveća egzokrina žlijezda u pasa sa središnjom ulogom u održavanju homeostaze
organizma. Bolesti jetre ili hepatopatije javljaju se kao akutne ili kronične, prirođene ili stečene te
primarne ili sekundarne. Klinički znakovi oboljenja javljaju se tek po gubitku većine jetrene
funkcionalne mase te su nespecifični, otežavajući tako pravovremeno postavljanje dijagnoze.
Dijagnostički pristup hepatobilijarnim bolestima treba biti sveobuhvatan, odnosno za postavljanje
sigurne dijagnoze potrebno je u obzir uzeti nalaze kliničkog pregleda, laboratorijskih pretraga krvi,
slikovne dijagnostike i patohistološke pretrage tkiva. U pasa su većina hepatobilijarnih oboljenja
nepoznate etiologije pa se liječenje bazira na upotrebi potporne i simptomatske terapije s ciljem
usporavanja progresije bolesti. Novija istraživanja pokazuju kako rana dijagnostika i
individualizirani pristup liječenju značajno poboljšavaju prognozu i kvalitetu života oboljelih
životinja. Stoga je cilj ovog rada obraditi i predstaviti sve učestalo korištene metode dijagnostike i
terapije bolesti jetre u pasa, s posebnim naglaskom na najčešće bolesti – kronični hepatitis,
hepatopatije povezane s bakrom, bolesti žučovodnog sustava i kongenitalni portosistemski šant.

Abstract (english)

The liver is the largest exocrine gland in dogs and plays a central role in maintaining the body's
homeostasis. Liver diseases, or hepatopathies, can be acute or chronic, congenital or acquired, and
primary or secondary. Clinical signs of liver disease appear only after the loss of most of liver's
functional mass and are non-specific, making it difficult to make a timely diagnosis. A
comprehensive diagnostic approach to hepatobiliary diseases is necessary, including clinical
examination findings, blood laboratory tests, diagnostic imaging and histopathological tissue
examination. In dogs, most hepatobiliary diseases are of unknown etiology, so treatment is based
on supportive and symptomatic therapy aimed at slowing progression of the disease. Recent
research indicates that early diagnosis and individualized treatment approach significantly improve
prognosis and quality of life in affected animals. Therefore, the aim of this paper is to present all
commonly used methods for diagnosing and treating liver diseases in dogs, with special emphasis
on the most common diseases – chronic hepatitis, copper-associated hepatopathies, biliary tract
diseases, and congenital portosystemic shunt.

• Keywords: jetra; žučovod; dijagnostika; terapija; hepatitis
• Keywords (english): liver; bile duct; diagnostic; therapy; hepatitis
• Language: croatian
• URN:NBN: urn:nbn:hr:178:834727
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2024-10-23 08:09:03