Promjene koncentracije kolesterola i triglicerida tijekom umjerenog treninga u labrador retrivera

master's thesis

• Title (english): Changes in Cholesterol and Triglyceride Concentrations during Moderate Training in Labrador Retrievers
• Author: Biljana Knežević
• Mentor: Maja Belić (mentor)
• Mentor: Zoran Vrbanac (mentor)
• Committee member: Damir Stanin
• Committee member: Maja Belić
• Committee member: Zoran Vrbanac
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2014-09-23, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Poznato je da vježbanje uzrokuje predvidljive fiziološke promjene sa odgovarajucim
izmjenama komponenti periferne krvi u mnogih vrsta. U nekim slucajevima, te promjene
odražavaju odgovarajuce fiziološke prilagodbe na zahtjeve koje postavlja samo vježbanje, dok
u drugim slucajevima one odražavaju patofiziološke abnormalnosti koje proizlaze od stresa
uzrokovanog vježbom. Hormonske promjene koje se zbivaju tijekom vježbanja utjecu na
sposobnost metabolizma da udovolji energetskim zahtjevima samog vježbanja. Izvori energije
osim glukoze su i masne kiseline koje se esterifikacijom skladište kao trigliceridi te služe kao
rezerva energije. Kolesterol se nalazi u sastavu stanicnih membrana, omogucuje prijenos tvari
u stanicu i iz nje, kao osnovni sastavni dio serumskih lipoproteina ima važnu ulogu u
transportu triglicerida i prekursor je žucnih kiselina koje se sintetiziraju u jetri i prijeko su
potrebne za apsorpciju masti u tankom crijevu. U ovom radu je mjerena koncentracija
triglicerida i kolesterola u krvi dvadeset pasa na pocetku te na kraju cetveromjesecnog
treninga, tijekom kojeg su psi bili podvrgnuti vježbanju na pokretnoj traci tri puta tjedno po
20 minuta. Koncentracija triglicerida je, osim kod dva psa, bila u granicama referentnih
vrijednosti, dok je koncentracija ukupnog kolesterola bila povišena kod osam pasa. Na kraju
cetveromjesecnog treninga uocen je blagi pad koncentracije triglicerida. Kod kolesterola
uoceno je statisticki znacajno sniženje vrijednosti ukupnog kolesterola na kraju treninga. Iako
su u cetiri psa ustanovljene više vrijednosti kolesterola od onih referentnih, one su u tri psa
ipak bile niže nego prije treninga. To se može pripisati povecanoj razgradnji kolesterola na
žucne kiseline koje ce dalje pomoci u njegovu otapanju i posljedicno njegovoj povecanoj
ekskreciji.

Abstract (english)

It is known that exercise causes predictable physiological changes with corresponding
changes in the components of the peripheral blood in many species. In some cases, these
changes reflect the appropriate physiological adaptation to the demands posed by just
exercising, while in the other cases they reflect pathophysiological abnormalities that result
from the stress caused by exercise. The hormonal changes that occur during exercise affect
the metabolism to cope with the energy demands of exercise. Energy sources other than
glucose are fatty acids, which are stored by esterification ti triglycerides, and server as a
reserve of energy. Cholesterol is a part of the cell membranes, allows the transfer of
substances in and out of the cell, as a basic component of serum lipoproteins play an
important role in the transport of triglycerides and is precursor of bile acids which are
synthesized in the liver and are essential to fat absorption in the small intestine. In this
investigation/study the concentrations of triglycerides and cholesterol were measured in the
blood of twenty dogs at the beginning and at the end of a four-month training, during which
the dogs were submitted to exercise on a treadmill three times a week for 20 minutes.
Triglycerides values were, except in the two dogs, within the reference range, while total
cholesterol concentration were higher in eight dogs. At the end of four-month training the
slight decrease in triglyceride concentration was shown. At cholesterol levels we have found
statistically significant fall of total cholesterol values at the end of the training. Even though
four dogs had higher values than the reference values, they were still in three dogs lower than
before the training. This can be explained by increased degradation of the cholesterol on bile
acids, further dissolvation and consequently increased excretion.

• Keywords: tjelovježba; trigliceridi; kolesterol; pas
• Keywords (english): exercise; triglyceride; cholesterol; dog
• Language: croatian
• URN:NBN: urn:nbn:hr:178:693802
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2016-01-12 12:16:42