KOMPARATIVNA ANALIZA OSJETLJIVOSTI NA ANTIMIKROBNE PRIPRAVKE BAKTERIJA IZDVOJENIH IZ PERADI I PTICA KUĆNIH LJUBIMACA

master's thesis

• Title (english): Comparative analysis of antimicrobial resistance in bacterial isolates from poultry and companion birds
• Author: Barbara Mratović
• Mentor: Željko Gottstein (mentor)
• Committee member: Liča Lozica (predsjednik povjerenstva)
• Committee member: Maja Lukač (član povjerenstva)
• Committee member: Željko Gottstein (član povjerenstva)
• Committee member: Danijela Horvatek Tomić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2023-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Public Health and Food Safety

Abstract

Rezistencija bakterija na antimikrobne pripravke predstavlja značajan problem u borbi protiv
bakterijskih infekcija kako kod životinja tako i kod ljudi. Najrelevantniji bakterijski patogeni
u peradarstvu koji su u svezi s AMR su bakterije Salmonella enterica, Campylobacter spp.
(najčešće C. jejuni), Escherichia coli, Enterococcus spp. i meticilin-rezistentan Staphylococcus
aureus (MRSA). Posljednjih godina također je prepoznata je potencijalna opasnost razvijanja
AMR kod ptica kućnih ljubimaca i sam prijenos rezistentnih sojeva bakterija na ljude. U svrhu
dobivanja vrijednih podataka o trendovima AMR peradi i ptica kućnih ljubimaca pretraženi su
rezultati antibiograma dobiveni testiranjem čistih kultura bakterija provedenih u razdoblju od
siječnja 2018.godine do prosinca 2022. godine u Bakteriološkom laboratoriju Zavoda za bolesti
peradi s klinikom. Dobiveni rezultati podudaraju se s rezultatima prijašnjih istraživanja
provedenih na području EU. Prisutnost i stupanj AMR sojeva E. coli za gotovo sve testirane
antimikrobne pripravke značajno veća kod tovnih purana i pilića u odnosu na kokoši nesilice.
Moguće je pratiti trendove korištenja antimikrobnih pripravaka i razliku u AMR na temelju
kategorije životinja (kokoši, tovni purani, pilići i ptice kućni ljubimci). Dobiveni rezultati
ukazuju na prisutnost AMR sojeva bakterija u RH kod peradi i ptica kućnih ljubimaca.

Abstract (english)

Antimicrobial resistance remains a significant issue in the fight against bacterial infections in
animals as well as in people. The pathogens most relevant in poultry industry, and associated
with AMR, include Salmonella enterica, Campylobacter spp. (most common C. jejuni),
Escherichia coli, Enterococcus spp. and methicillin-resistant Staphylococcus aureus. (MRSA).
In the last decade the threat of emergence of AMR and potential of antimicrobial resistant
bacteria spreading to pet owners in companion birds has been noted. In order to obtain valuable
data on trends of AMR in poultry and companion birds, results of antibiograms of bacterial
isolates were carried out in period from January 2018. to December 2022. at Bacteriological
laboratory of the Poultry diseases department with clinic were searched. The obtained results
coincide with the results of previous research conducted in the EU. The prevalences and
degrees of antibiotic resistance for E. coli serovars for nearly all antibiotics tested were
significantly higher in the turkey and broiler populations, compared with laying hens. It is
possible to track trends in antimicrobial use and differences in AMR based on animal category
(laying hens, turkeys, broilers and companion birds). The obtained results indicate the presence
of AMR strains of bacteria in the Republic of Croatia in poultry and companion birds.

• Keywords: Rezistencija bakterija na antimikrobne pripravke; perad; ptice kućni ljubimci rezultati antibiograma
• Keywords (english): antimicrobial resistance; poultry; companion birds; antibiogram results
• Language: croatian
• URN:NBN: urn:nbn:hr:178:004653
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-11-13 09:23:48