PREVALENCE OF FELINE CARDIOMYOPATHIES AT THE CLINIC FOR INTERNAL DISEASES OF THE VETERINARY FACULTY OF ZAGREB FROM 2017 TO 2022

master's thesis

• Title (croatian): Pretežitost pojave mačjih kardiomiopatija u Klinici za unutarnje bolesti Veterinarskog fakulteta Sveučilišta u Zagrebu u razdoblju od 2017. do 2022. godine
• Author: Elise Farah
• Mentor: Marin Torti (mentor)
• Committee member: Iva Šmit (predsjednik povjerenstva)
• Committee member: Marin Torti (član povjerenstva)
• Committee member: Gabrijela Jurkić Krsteska (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-07-05, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Cardiomyopathies represent the most important cardiac disease in cats, and hypertrophic
cardiomyopathy is by far the prevailing phenotype. This mainly idiopathic condition affects
primarily older and male cats of mixed breed. However, some breeds, such as Maine Coon and
Ragdoll, have a predisposition, linked to a mutation. Congestive heart failure and arterial
thromboembolism are two fatal consequences, and are responsible for the presenting symptoms,
when cats are not subclinical. The gold standard for diagnosis is echocardiography, which
additionally allows for differentiation between the five different phenotypes. Clinical staging
can guide veterinarians in establishing a management and treatment protocol, as well as
assessing the prognosis. This retrospective study aims to analyse the prevalence and other trends
associated to this feline disorder at the clinic for internal diseases in the Veterinary Faculty of
Zagreb over a 5-year period. Data about epizootiology, presentation and diagnosis to name a
few was collected and examined. Overall, most findings are coherent with results from previous
research.

Abstract (croatian)

Kardiomiopatije predstavljaju najvažniju skupinu stečenih srčanih bolesti u mačaka.
Hipertrofična kardiomiopatija najčešći je oblik kardiomiopatije u mačaka. Općenito govoreći,
kardiomiopatije su idiopatske bolesti miokarda koje prvenstveno pogađaju starije i muške
mačke. Opisane su i pasminske predispozicije, tako da se hipertrofična kardiomiopatija javlja
u pashmina Maine Coon i Ragdoll, a povezana je sa specifičnom genskom mutacijom. Akutno
popuštnje (kongestivno zatajivanje) srca i arterijska tromboembolija dva su tipična klinička
scenarija kojima se kardiomiopatije očituju. Dijagnostički zlatni standard je ehokardiografija,
koja dodatno omogućuje diferencijaciju između pet različitih fenotipova. Kliničko stupnjevanje
kardiomiopatija korisno je u standardizaciji pristupa liječenju, ali i prognoziranju ishoda bolesti.
Prikazano retrospektivno istraživanje ima za cilj analizirati pretežitost pojave kao i druge
pokazatelje kardiomiopatija u populaciji mačaka zaprimljenih u Klinici za unutarnje bolesti
Veterinarskog fakulteta u Zagrebu Sveučilišta u Zagrebu, tijekom petogodišnjeg razdoblja.
Prikupljeni su te istraženi podatci o epizootiologiji, kliničkoj slici i dijagnostičkoj obradi.

• Keywords: hypertrophic cardiomyopathy; echocardiography; prevalence; retrospective study; cat
• Keywords (croatian): hipertrofična kardiomiopatija; ehokardiografija; pretežitost; retrospektivno istraživanje; mačka
• Language: english
• URN:NBN: urn:nbn:hr:178:042673
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-07-16 08:59:09