Osnove nasljeđivanja boje dlake pasa

master's thesis

• Title (english): BASICS OF DOG COAT COLOUR INHERITANCE
• Author: Lara Peleš
• Mentor: Anamaria Ekert Kabalin (mentor)
• Mentor: Maja Maurić Maljković (mentor)
• Committee member: Velimir Sušić (predsjednik povjerenstva)
• Committee member: Sven Menčik (član povjerenstva)
• Committee member: Anamaria Ekert Kabalin (član povjerenstva)
• Committee member: Maja Maurić Maljković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Animal Production and Biotechnology

Abstract

Čovjek je dugotrajnom i pažljivom selekcijom uzgojio pasmine kakve danas poznajemo.
Poznavanje genetike postalo je izrazito bitno, posebno za uzgajivače, kako bi znali ustanoviti
kombinacije potrebne za dobivanje željenih svojstava, odnosno kako bi minimalizirali
nepoželjna svojstva. Boja dlake pasa oduvijek je bila zanimljivo područje, kao jedno od prvih
vidljivih odlika životinje. Ljudi su počeli sve više cijeniti rijetke boje ili čak nove obrasce
njihove pojave te nijanse kod određenih pasmina. Melanin je osnovni pigment, koji se očituje
u 2 oblika: eumelanin i feomelanin. Eumelanin predstavlja tamnije tonove, dok je feomelanin
žuto-crvene boje. Tri glavna gena kontroliraju izmjenu eumelanina i feomelanina, a to su ASIP,
MC1R i CBD103, te njihova interakcija određuje osnovnu boju jedinke. Na osnovnu boju mogu
djelovati i mnogobrojni drugi geni, kao što su gen za razrijeđenje boje ili geni koji uzrokuju
pojavu specifičnih uzoraka. Utvrđena je uzročno-posljedična veza između pigmentacije i
određenih patoloških stanja kao što su albinizam, alopecija posredovana razrjeđenjem i gluhoća
kod životinja s merle uzorkom. Stoga novija istraživanja stavljaju naglasak na dobrobit
životinja u cilju stvaranja cjelovite genske sekvence koja bi olakšala razumijevanje ovog
područja te omogućila smanjenje pojave bolesti u uzgojnom radu.

Abstract (english)

Through long-term and careful selection, humans have bred the breeds we know today.
Understanding genetics has become extremely important, especially for breeders, to determine
the combinations needed to achieve desired traits and to minimize undesirable ones. The color
of a dog's coat has always been an interesting area and one of the first visible characteristics of
the animal. People have increasingly valued rare colors or even new patterns and shades for
specific breeds. Coat color in dogs is a complex area involving many genes and their
interactions. Melanin is the basic pigment and manifests in two forms: eumelanin and
pheomelanin. Eumelanin represents darker tones, while pheomelanin is yellow-red in color.
Three main genes control the exchange of eumelanin and pheomelanin: ASIP, MC1R, and
CBD103, and their interaction determines the base color of the individual. Many other genes
can also affect the base color, such as the gene for dilution or other genes that cause specific
patterns. A causal relationship has been established between pigmentation and certain
pathological conditions such as albinism, colour dilution alopecia, and deafness in animals with
the merle pattern. Therefore, recent research emphasizes aimal welfare with the aim of creating
a complete genetic sequence that would facilitate understanding in this field and reduce the
occurrence of diseases in breeding practices.

• Keywords: pas; boja; pigmentacija; genetika; nasljeđivanje
• Keywords (english): dog; color; pigmentation; genetics; inheritance
• Language: croatian
• URN:NBN: urn:nbn:hr:178:118755
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-25 12:29:58