Metabolički poremećaji kod pretilih pasa i mačaka

master's thesis

• Title (english): Metabolic Disorders in Overweight Dogs and Cats
• Author: Lucija Lemac
• Mentor: Renata Barić Rafaj (mentor)
• Committee member: Josipa Kuleš (predsjednik povjerenstva)
• Committee member: Jasna Aladrović (član povjerenstva)
• Committee member: Renata Barić Rafaj (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2025-02-21, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Basic and Preclinical Veterinary Sciences

Abstract

Metabolički poremećaji kod pretilih pasa i mačaka
Pretilost je bolest modernog doba. U sve većoj prevalenciji se javlja kod najčešćih
kućnih ljubimaca, pasa i mačaka. Masno tkivo koje se nakuplja kada jedinka postane pretila je
endokrinološki aktivno te na taj način utječe na mnoge procese u organizmu. Tvari koje masno
tkivo luči zajedničkim imenom nazivamo adipokini. Adipokini svojim pretjeranim ili
smanjenim lučenjem te međusobnom interakcijom pogoduju razvoju raznih metaboličkih
poremećaja.
U ovom radu su opisani poremećaji koji su najbitniji i najbolje istraženi kod pasa i
mačaka. To su šećerna bolest, dislipidemija, metabolički sindrom, hipertenzija, ateroskleroza,
osteoartritis te je veća pojavnost raznih neoplazija. Za većinu ovih stanja je potrebno provesti
dodatna istraživanja ali zasada su postavljeni temelji za razumijevanje važnosti i utjecaja
pojedinih adipokina na razvoj ovih metaboličkih poremećaja vezanih uz pretilost. Dodatnim
istraživanjima će se olakšati rana dijagnostika metaboličkih poremećaja te će se lakše moći
razlikovati jesu li ti poremećaji primarno nastali zbog pretilosti. Na taj način će se bolje moći
sanirati i prevenirati daljnja progresija patologija vezanih uz pretilost.
Također, psi i mačke bi se u budućnosti sve više mogli koristiti za istraživanje
metaboličkih poremećaja kod pretilih ljudi.

Abstract (english)

Obesity is a modern age disease. Prevalence of obesity is increasing in cats and dogs
which are most common pets. Adipose tissue that accumulates in obease individuals is
endocrinologically active and thus affects many mechanisms in the body. The substances
secreted by adipose tissue are called adipokines. Adipokines, with their excessive or reduced
secretion and mutual interaction, favor the development of various metabolic disorders.
Those that are most important and best reaserched in dogs and cats are described in this
paper. These metabolic disordes are diabetes mellitus, dyslipidemia, metabolic syndrome,
hypertension, atheroslcerosis, osteoarthritis, and a higher incidence of various neoplasias. For
most of these conditions, it is necessary to carry out additional research, but so far foundational
information are provided for understanding the importance and influence of each adipokine on
the development of these disorders. Additional research will facilitate the early diagnosis of
metabolic disorders and it will be easier to distinguish whether these disorders are primarily
due to obesity. This way, it will be possible to treat and prevent the further progression of
obesity-related pathologies.
In the future, dogs and cats could be used more often as a model for researching obesity
in humans

• Keywords: pretilost; pas; mačka; masno tkivo; adipokini; metabolički poremećaj
• Keywords (english): obesity; cat; dog; adipose tissue; adipokines; metabolic disorder
• Language: croatian
• URN:NBN: urn:nbn:hr:178:352182
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2025-03-03 10:09:57