Učestala klinička dijagnostika u kunića sa neurološkim simptomima

master's thesis

• Title (english): Frequent Clinical Diagnostics in Rabbits with Neurological Signs
• Author: Valentina Šilić
• Mentor: Mirna Brkljačić (mentor)
• Committee member: Ivana Kiš
• Committee member: Iva Šmit
• Committee member: Mirna Brkljačić
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Internal Diseases Clinic); Zagreb
• Defense date and country: 2016-03-18, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Pastereloza i encefalitozoonoza kunića predstavljaju najčešće bolesti koje se mogu manifestirati neurološkim simptomima, a njihova diferencijalna dijagnostika predstavljaja veliki izazov u svakodnevnom radu kliničara.
Encephalitozoon cuniculi je obligatni unutarstanični protozoarni parazit, uzročnik je encefalitozoonoze. Klinička slika bolesti je vrlo raznolika i uključuje simptome od strane tri različita organska sustava: neurološkog, oftalmološkog i mokraćnog.
P. multocida je vrlo često izolirana bakterija u kunića, a iznimno uzrokuje primarnu bolest. Uzrokuje infekcije brojnih organskih sustava, prvenstveno respiratornog sustava. Najčešća lokalizacija bakterije je u sinusima, eustahijevoj tubi, srednjem uhu, nazolakrimalnim kanalima, treheji i plućima. Istraživanje je obuhvatilo 35 kunića liječenih na Klinici za unutarnje bolesti Veterinarskog fakulteta u Zagrebu u razdoblju od 1. siječnja 2012. do 1. siječnja 2016. kojima je tijekom dijagnostičke obrade izdvojena P. multocida ili postavljena radna dijagnoza encefalitozoonoze.
Na temelju rezultata ovog istraživanja došli smo do zaključka da ženke češće oboljevaju od pastereloze, a mužjaci od encefalitozoonoze. Obje bolesti najčešće se javljaju u kunića srednje dobi, starih između 1-5 godina života. Najučestaliji simptom kod obje bolesti bio je „head tilt“ dok je nistagmus zabilježen samo kod encefalitozoonoze. Kunići s pasterelozom imali su ispoljene respiratorne i oftalmološke simptome puno češće nego kunići s encefalitozoonozom.

Abstract (english)

Pasteurellosis and encephalitozoonosis are common diseases in rabbits manifested with neurological symptoms. Differentiation between these two diseases may represent an issue in veterinarian clinics. Encephalitozoon cuniculi is an obligatory intracellular microsporidial organism which causes encephalitozoonozis. Clinical manifestation is very diverse -central nervous system, kidneys and eyes are predilection sites in rabbits. P. multocida is commonly isolated bacteria in rabbits, it is an opportunistic organism. The most common presentations are rhinitis, conjunctivitis, pneumonia, otitis media, otitis interna, infection of nasolacrimal duct and trachea. This study included 35 rabbits diagnosed with either pasterellosis or encephalitozoonosis treated at the Clinic for Internal Disease, Faculty of Veterinary Medicine in Zagreb, between 1st January 2012 and 1st January 2016. Based on the results of our study, we concluded that there is a predisposition for females to be infected with pasteurellosis, and for males with encephalitozonosis. The most common clinical symptom of both diseases was head tilt while nistagmus was present only in rabbits diagnosed with encephalitozoonosis. While rabbits with pasterellosis more frequently had respiratory and ophtalmologic signs in compared to rabbits with encephalitozoonosis.

• Keywords: kunići; neurološki simptomi; encefalitozoonoza; P. multocida
• Keywords (english): rabbits; neurological symptoms; encephalitozoonosis; P. multocida.
• Language: croatian
• URN:NBN: urn:nbn:hr:178:011044
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2016-04-11 10:21:23