Primjena pentadekapeptida BPC 157 u prihranjivanju pčelinjih zajednica

master's thesis

• Title (english): Appliance of Pentadecapeptid BPC-157 in Additional Feeding of Honeybee (Apis Mellifera)
• Author: Matea Vodanović
• Mentor: Ivana Tlak Gajger (mentor)
• Committee member: Srebrenka Nejedli (predsjednik povjerenstva)
• Committee member: Josipa Vlainić (član povjerenstva)
• Committee member: Ivana Tlak Gajger (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Department for Biology and Pathology of Fish and Bees); Zagreb
• Defense date and country: 2016-09-21, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine

Abstract

Medonosnu pčelu (Apis mellifera) smatra se najpogodnjom vrstom pčela za suvremeni način pčelarenja zbog njezinih dobrih bioloških i proizvodnih osobina. Nozemoza je nametnička bolest pčela uzrokovana mikrosporidijama Nosema apis i Nosema ceranae. Nozemoza tipa C izrazito je patogena bolest kroničnog tijeka s dugim inkubacijskim razdobljem, a najčešće prolazi asimptomatski ili se manifestira nespecifičnim simptomima poput postepenog slabljenja pčelinjih zajednica, povećanog stupnja ugibanja odraslih pčela i posljedično smanjenja proizvodnje meda. Zbog asimptomatske prirode, izrazite patogenosti kao i zabranjene uporabe antibiotika, nozemoza tipa C predstavlja ozbiljan problem u suvremenom pčelarstvu. Obzirom na ovu problematiku, danas su znanstvena istraživanja usmjerena na ispitivanje učinkovitosti prirodnih tvari u kontroliranju i suzbijanju nozemoze. BPC 157 je visoko stabilan protein koji se koristi bez nosača, sistemski i lokalno. Dosadašnja istraživanja na sisavcima su pokazala da znatno unaprjeđuje cijeljenje različitih tkiva. Stoga je cilj ovoga rada bio utvrditi utjecaj primjene pentadekapeptida BPC 157 u obliku dodatka hrani tijekom jesenskog prihranjivanja na broj spora N. ceranae, a s pretpostavkom o mogućem utjecaju na zacjeljivanje mikro oštećenja srednjeg crijeva medonosne pčele.

Abstract (english)

Honeybee (Apis mellifera) is considered one of the most favorable species of bees for modern way of beekeeping because of her good biological and producing characteristics. Nosemosis is a parasitic disease of adult honeybees, caused by microsporidia Nosema apis and Nosema ceranae. Nosemosis type C is a significantly pathogenic disease with chronic course and long incubation period, which usually passes asymptomatically or manifests by nonspecific symptoms like gradual weakening of honeybee colonies, enhanced loss of adult bees and decreased production of honey. Because of asymptomatic nature, significant pathogenic and prohibited use of antibiotics, nosemosis type C represents serious problem in modern beekeeping. Regarding this issues, the researches today are focused on determination of effectiveness of natural supstances in controlling and combating nosemosis. BPC 157 is a high stable protein, which is used without carrier, systematically and locally. The researchers on mammals showed that it considerably enhances healing of different matter. So, the aim of this research was to determine the effect of applying pentadecapeptide 157 as food supplement during autumn additional feeding on a number of N. ceranae spores, and with presumption about possible effect on healing micro damages of honeybee middle intestine.

• Keywords: medonosna pčela; nozemoza; BPC 157.
• Keywords (english): honey bee; nosemosis; BPC 157.
• Language: croatian
• URN:NBN: urn:nbn:hr:178:334234
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-07-23 10:01:00