Kako istraživati antimikrobnu učinkovitost tvari prirodnog porijekla

master's thesis

• Title (english): How to Test Antimicrobial Activity of Natural Products
• Author: Domagoj Trninić
• Mentor: Jelena Šuran (mentor)
• Mentor: Josipa Vlainić (komentor)
• Committee member: Frane Božić (predsjednik povjerenstva)
• Committee member: Jelena Šuran (član povjerenstva)
• Committee member: Andreja Prevendar-Crnić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Department of Pharmacology and Toxicology); Zagreb
• Defense date and country: 2020-05-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Public Health and Food Safety

Abstract

Zarazne bolesti uzrokovane bakterijama, gljivama, virusima i parazitima predstavljaju opasnost za javno zdravlje. Iako postoje brojni antimikrobni lijekovi, danas je potraga za novim supstancama s antimikrobnim djelovanjem sve intenzivnija posebice s obzirom na razvoj rezistentnih sojeva, te zbog nedostupnosti lijekova u siromašnim zemljama. Naime, biološka raznolikosti i postojanje brojnih prirodnih produkata, koje nalazimo kao čiste tvari ili kao standardizirane ekstrakte, su brojni što daje veliku mogućnosti pronalaska adekvatnog lijeka.
Istraživanje antimikrobnog djelovanja prirodnih pripravaka nužno treba biti standardizirano kao i samo dobivanje ekstrakata. U ovom se preglednom radu iznose preporuke za stvaranje okvira istraživanja antibakterijskih, antivirusnih, antiparazitskih i antivirusnih učinaka prirodnih pripravaka.

Abstract (english)

Infectious diseases caused by bacteria, fungi, viruses and parasites pose a threat to public health. Although there are numerous antimicrobials, the search for new antimicrobial substances is increasingly intensified, especially with regard to the development of resistant strains and the unavailability of drugs in poor countries. Biodiversity and the existence of numerous natural products, which are found as pure substances or as standardized extracts, are numerous, which gives a great opportunity to find an adequate drug. Research of the antimicrobal activity of natural substances needs to be standardized as well as the extraction itself. With this review graduate thesis we give recommendations for the research of antibacterial, antifungal, antiparasite and antivirus effect of natural products.

• Keywords: zarazne bolesti; bakterije; gljive; virusi; paraziti; javno zdravlje; antimikrobni lijekovi
• Keywords (english): infectious diseases; bacteria; fungi; viruses; parasites; public health; antimicrobial drugs
• Language: croatian
• URN:NBN: urn:nbn:hr:178:126184
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-10-15 09:00:47