Sindrom zaostalog jajnika kod kuje

master's thesis

• Title (english): Ovarian Remnant Syndrome
• Author: Dora Žučko
• Mentor: Nino Maćešić (mentor)
• Mentor: Martina Lojkić (mentor)
• Committee member: Ivan Folnožić (predsjednik povjerenstva)
• Committee member: Goran Bačić (član povjerenstva)
• Committee member: Nino Maćešić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Reproduction and Obstetrics Clinic); Zagreb
• Defense date and country: 2017-06-30, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Ovarijektomija i ovariohisterektomija najčešće su izvođeni kirurški zahvati u veterinarskoj medicini. Mogu biti terapijska metoda različitih patoloških stanja koja zahvaćaju reproduktivni sustav, no većinom se izvode u svrhu elektivne kastracije s ciljem sprječavanja neželjenog potomstva. Zbog rutinskog izvođenja ovih zahvata značajnije postoperativne komplikacije su rijetke. Sindrom zaostalog jajnika jedna je od komplikacija ovariohisterektomije, a javlja se u razmjerno visokom postotku slučajeva. Glavni razlog pojave je neuspješno uklanjanje cijelog jajnika, a zaostale količine tkiva se nakon nekog vremena revaskulariziraju i ponovno postaju funkcionalne. Hormonski aktivno tkivo proizvodi estrogen i uzrokuje simptome estrusa kao i kod intaktnih jedinki – edem stidnice, sangvinozni iscjedak iz rodnice te tipično aktivno i pasivno ponašanje. Gotovo uvijek zaostaje tkivo u području desne peteljke jajnika zbog teže dostupnosti kirurgu. Dijagnoza se temelji na detaljnom uzimanju anamneze i vaginalnoj citologiji, a u potvrđivanju sumnje pomažu i mjerenja koncentracija spolnih hormona, provokativno testiranje gonadotropnim releasing hormonom ili humanim korionskim gonadotropinom te mjerenje Anti-Müllerova hormona. Najpouzdaniji način je dijagnostička laparotomija koja se danas, zbog dostupnosti manje invazivnih metoda, nastoji reducirati u upotrebi. Mogućnosti liječenja hormonskom terapijom su ograničene i nisu preporučene za dugoročnu dobrobit životinje. Liječenje izbora je kirurška ekscizija zaostale mase, što može biti zahtjevan postupak zbog nedostupnosti tkiva. Budući da je incidencija pojave zloćudnih tumora spolnog sustava visoka u jedinki sa ovim sindromom, u svrhu prevencije i pravodobne dijagnostike izrezano tkivo se uvijek upućuje na patohistološku pretragu.

Abstract (english)

Ovariectomy and ovariohysterectomy are most commonly performed surgical procedures in veterinary medicine. Although they serve as a therapeutical method of various pathological conditions which affect reproductive system, in most cases their purpose is elective castration to prevent unwanted litter. Due to routine performance, significant postoperative complications are rare with these procedures. Ovarian remnant syndrome is an iatrogenic caused condition which occurs in relatively high percentages as a complication after ovariohysterectomy. Main reason for this occurance is inability to remove the whole ovary so remaining ovarian tissue revascularizes over time and retrieves its full function. Active tissue produces estrogen and causes same symptoms of heat as in an intact female – vulvar swelling, sanguinosus vaginal discharge and typical active or passive behaviour. In most cases remnant is found near right ovarian pedicle because the position is hard to reach during surgery. Diagnosis is based on thorough anamnesis and vaginal cytology. Measuring circulating levels of ovarian streoids, provocative GnRH or HCG testing and concentration of Anti-Müllerian hormone are used as an additional confirmation. Most reliable way of successfully diagnosing this syndrome is a diagnostic laparotomy but due to the progress of minimal invasive surgical techniques, its usage is nowdays significantly reduced. Hormone treatment is limited and not recommended long term. Treatment of choice is surgical excision of the remaining mass which can be difficult because the tissue is often inapproachable. Considering high rate of malignant changes accompanying this condition, excised tissue is always sent to patohystological examination in order to prevent and diagnose possible life-threatening neoplasias in timely manner

• Keywords: kuja; kastracija; zaostali jajnik
• Keywords (english): bitch; castration; ovarian remnant syndrom
• Language: croatian
• URN:NBN: urn:nbn:hr:178:352304
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-11-27 10:46:25