Mjerenje mineralne gustoće kosti u životinja

master's thesis

• Title (english): Measuring of the Bone Mineral Density in Animals
• Author: Petar Špiljar
• Mentor: Hrvoje Lucić (mentor)
• Mentor: Hrvoje Brzica (komentor)
• Committee member: Snježana Vuković (predsjednik povjerenstva)
• Committee member: Damir Mihelić (član povjerenstva)
• Committee member: Hrvoje Lucić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Department of Anatomy, Histology and Embriology); Zagreb
• Defense date and country: 2016-03-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Basic and Preclinical Veterinary Sciences

Abstract

Mjerenje mineralne gustoće kosti u širokoj je kliničkoj upotrebi u humanoj medicini, prvenstveno u dijagnostici osteopenija. U veterinarskoj medicini, najviše se koristi u eksperimentalne svrhe u smislu istraživanja osteoporoze na modelima životinja, ali se počinje primjenjivati i u kliničkoj praksi kod praćenja procesa ozdravljenja od bolesti koštanog tkiva. Osim toga, u literaturi se pojavljuje sve više opisa istraživanja koja prate promjene mineralne gustoće kosti u životinja ovisno o dobi i spolu sa sličnim zaključcima kakvi su zabilježeni u ljudi. Rad obrađuje dostupne literaturne podatke, te daje pregled dosadašnjih istraživanja i primjene mjerenja mineralne gustoće kosti u životinja. Mjerenje mineralne gustoće kosti u životinja provodi se isključivo na humanim uređajima uz prilagodbu položaja tijela životinje. Male laboratorijske životinje, štakor i miš, najviše se koriste kao animalni model za istraživanje osteopenija ljudi. Pas kao animalni model, najviše se koristi kod praćenja zaraštavanja prijeloma i okoštavanja oko implantata. Od velikih životinja ovce su najčešći model za istraživanje osteoporoze. Na dupinima se osteodenzitometrija istražuje kao alternativna metoda za procjenu dobi životinja.

Abstract (english)

Measurement of the bone mineral density is in the wide clinical use in human medicine, especially in the diagnosis of osteopenia. In veterinary medicine, it is used for experimental purposes in terms of research on animal models of osteoporosis mostly, but its begin to be apply in clinical practice in monitoring of the healing process of bone tissue diseases. In addition, in the literature appears more description studies which monitor the changes in bone mineral density of animals depending on the age and gender with similar conclusions earlier described in men. This paper deals with the available literature data, and provides an overview of current research and application of measurement of bone mineral density in animals. Measurement of bone mineral density in animals is carried out exclusively on human devices with the adjustment of the animal body. Small laboratory animals, rat and mouse, are used mostly as animal model for researching of osteopenia in people. The dog as an animal model is mostly used in monitoring of overgrowth fractures and ossification around the implant. Between large animals, sheep are the most common model for the study of osteoporosis. In dolphins, the osteodensitometry is investigated as an alternative method for estimating of the animal age.

• Keywords: mineralna gustoća kosti; osteodenzitometrija; animalni modeli
• Keywords (english): bone mineral density; osteodensitometry; animal models
• Language: croatian
• URN:NBN: urn:nbn:hr:178:488903
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-11-27 11:13:54