Otrovi morskih organizama

master's thesis

• Title (english): Marine Biotoxins
• Author: Fran Šimac
• Mentor: Andreja Prevendar-Crnić (mentor)
• Committee member: Emil Srebočan (predsjednik povjerenstva)
• Committee member: Jelena Šuran (član povjerenstva)
• Committee member: Andreja Prevendar-Crnić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Department of Pharmacology and Toxicology); Zagreb
• Defense date and country: 2020-09-04, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Public Health and Food Safety

Abstract

Otrovi morskih organizama uzrokuju otrovanja ptica, riba i ljudi te ekološke i ekonomske probleme. Cilj ovog rada je detaljan opis najčešćih otrova morskih organizama i prikaz opisanih slučajeva otrovanja diljem svijeta, kako bi se informirala javnost o opasnostima i rizicima od kontaminiranih morskih plodova. Otrovanje je posljedica ingestije kontaminiranih školjkaša i riba iz komercijalnih izvora ili rekreacijskog sakupljanja. U ovome radu opisani su otrovi koji se najčešće nalaze u Europskom području sa naglaskom na Mediteransko more i drugdje u svijetu. Opisani su saksitoksini (STX), tetrodotoksini (TTX), domoična kiselina (DA) i analozi, okadaična kiselina (OA) i derivati, yessotoksini (YTX), azaspirna kiselina (AZA), pektenotoksini (PTX), ciklički imini te palitoksin (PLTX) i analozi, ciguatoksini (CTX), maitotoksini (MTX) i brevetoksini (PbTx). Za svaki od navedenih objašnjena je toksokinetika, mehanizam toksičnog djelovanja, eksperimentalna toksičnost, klinička slika, liječenje, analitičke metode i dopuštene koncentracije.

Abstract (english)

Marine biotoxins causes poisoning of birds, fish and people, as well as environmental and economic problems. The aim of this paper is a detailed description of the most common toxins of poisonous marine organisms with described cases worldwide, in order to inform the public about the dangers and risks of contaminated seafood. Poisoning is the result of ingestion of contaminated shellfish and fish from commercial sources or recreational collection. This paper describes poisons found in European area with an emphasis on the Mediterranean Sea and elsewhere in the world. Saxitoxins (STX), tetrodotoxins (TTX), domoic acid (DA) and analogs, okadaic acid (OA) and derivatives, yessotoxins (YTX), azaspiric acid (AZA), pectenotoxins (PTX), cyclic imines, palytoxin (PLTX) and analogs, ciguatoxins (CTX), maitotoxins (MTX) and brevetoxins (PbTx) have been described. Toxokinetics, toxicity mechanism, experimental toxicity, clinical signs, treatment, analytical methods and permissible concentrations were explained for each of the above.

• Keywords: otrovi morskih organizama; školjkaši; ribe; Mediteransko more; kontaminirani morski plodovi
• Keywords (english): marine biotoxins; shellfish; fish; Mediterranean Sea; contaminated seafood
• Language: croatian
• URN:NBN: urn:nbn:hr:178:813171
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-12-09 19:26:53