Prevalence of different types of corneal ulcers in dogs-retrospective study

master's thesis

• Title (croatian): Prevalencija različitih tipova ulkusa rožnice kod pasa - Retrospektivna studija
• Author: Capucine Fanny Justine Loire
• Mentor: Valentina Plichta (mentor)
• Committee member: Dražen Vnuk (predsjednik povjerenstva)
• Committee member: Andrija Musulin (član povjerenstva)
• Committee member: Valentina Plichta (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-07-09, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Corneal ulcers are one of the most often encountered pathology in canine patient in
everyday practice. They vary widely in terms of characteristics and etiologies. It is important
for clinicians to characterize and appropriately treat this variety of corneal ulcers as they can
lead to vision impairment, and even loss of the globe
This study aimed to establish descriptive statistics for 25 canine patients presented at
the Clinic for Surgery, Orthopaedics and Ophthalmology of with corneal ulcerations. Specific
goals are to characterize populations of dogs affected by ulcerative keratitis in Croatia, and to
comprehend treatment strategies adopted against different types of ulcers.
In this retrospective analysis in all of admitted patient during this thorough
ophthalmological examination with fluorescein test and STT-1 was perfomed. Patient data
regarding were sex, age, breed, type of corneal ulcer, status of patient (primary care or referral),
choice of treatment and length of treatment were collected and processed in Microsoft excel for
descriptive statistics.
Dogs meeting inclusion criteria were 25, 56% of them were males and 44% of them
were considered from brachycephalic breeds with French Bulldog being overrepresented. Mean
age was 7.36±3.09 years old. The main type of ulcer encountered in this study was SCCED
(44%) followed by simple superficial ulcers (24%). Mean STT-1 value was 20.2±7.99 mm/min.
Primary causes were difficult to establish but KCS and trauma were the most often encountered.
All dogs were treated with a topical antibiotic (tobramycin or ciprofloxacine). Other prescribed
medications included received pain control medications, cyclosporine, artificial tears and/or
proteases inhibitors. 16.7% of them received diamond burr debridement at first visit and 20.8%
during control visits. Only one case of keratomalacia lead to corneal perforation.
Good outcome of treatment with proper antimicrobial and other supportive therapy
based on ophthalmological examination results is important and can be expected in treating this
condition.

Abstract (croatian)

Čir rožnice jedno je od najčešćih oftalmoloških promjena kojima se možemo susresti u
svakodnevnoj praksi. Prema uzroku nastanka te dubini zahvaćenosti ozljede postoji više oblika,
Zbog razvoja mogućih komplikacija poput gubitka vida ili čak gubitka samog oka vrlo je važno
prepoznati te odgovarajuće liječiti pojedine oblike ove bolesti.
Cilj ovog istraživanja bilo je utvrditi prisutnost pojednih oblika čira rožnice te
raspodjelu podataka u zahvaćenoj populaciji zaprimljenih pasa na Kliniku za Kirurgiju,
ortopedij ui oftalmologiju Sveučilišta u Zagrebu. Specifični ciljevi uključuju zastupljenost
pojedinih pasmia pasa te ustanoviti odgovarajuću terapiju za zahvaćene pse u Republici
Hrvatskoj.
U ovom retrospektivnom istraživanju svih uključenim psima učinjen je detaljan
oftalmološki pregled uz test oštećenja rožnice flouresceinskom bojom te STT-1. Podaci o
životinjama poput spola, dobi, pasmini, vrsti čira rožnice, priarnoj ili referalnoj obradi, te dužini
trajanja liječenja obrađene su u programu Microsoft excel.
U populaciji pasa uključenih u istraživanje 25, 56% čini su muški psi, a 44% njih bilo
je brahiocefalične pasmine među kojima je najčešća pashmina bila Francuski bulldog.
Prosječna dob je bila 7.36±3.09 godina. Najčešći tip čira rožnice u istraživanju bio je SCCED
(44%) a zatim površinski čirevi (24%). Srednja vrijednost STT-1 u instraživanju iznosi
20.2±7.99 mm/min. Primarni uzrok bolesti teško se jasno uočava no KCS I trauma oka se
najčešće susreću. Svi psi su liječeni lokalnom primjenom antibiotika (tobramicina ili
ciprofloksacina). Uz navedene lijekove u liječenju su se koristili lijekovi protiv bolova,
ciklosporinm umjetne suze te inhibitori proteinaza za lokalnu promjenu.. 16.7% pacijenata
zahtjevalo je lokalni debridman rožnice dijamantnom brusilicom pri primarnom te 20.8% na
kontrolnom prelgedu. Samo jedan slučaj keratomalacije doveo je do perforacije rožnice.
Povoljan ishod liječenja s odgovoarajućim antimikrobnim pripravcima te uz ostalu terapiju
ovisno o rezultatima oftalmološkog pregleda može se očekivati u ovakvim slučajevima.

• Keywords: corneal ulcers; dogs; retrospective study; fluorescein test; Croatia
• Keywords (croatian): ulkusi rožnice; psi; retrospektivna studija; fluoresceinski test; Hrvatska
• Language: english
• URN:NBN: urn:nbn:hr:178:526858
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-07-15 12:16:34