Prirođene srčane grješke u pasa: prevalencija, dijagnostika i liečenje

master's thesis

• Title (english): Congenital Heart Defects in Dogs: Prevalence, Diagnosis and Treatment
• Author: Nicol Dobrić
• Mentor: Marin Torti (mentor)
• Committee member: Iva Šmit (predsjednik povjerenstva)
• Committee member: Mirna Brkljačić (član povjerenstva)
• Committee member: Marin Torti (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; (Internal Diseases Clinic); Zagreb
• Defense date and country: 2019-09-27, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Prirođene srčane grješke su grješke u anatomskog građi struktura srca, a prisutne su pri rođenju životinje. Uzrokuju ih genetski, farmakološki, toksični i drugi čimbenici. Prevalencija je 0,25 %, a postoji i pasminska predispozicija za pojavu prirođenih srčanih grješaka. U pasa se najčešće javljaju patentni ductus arteriosus, pulmonalna stenoza i subaortalna stenoza, a rijeđe ventrikulski septalni defekt, displazije srčanih zalistaka, perzistentni desni aotalni luk, atrijski septalni defekt i tetralogija Fallot. Najvažnije kliničko obilježje prirođenih srčanih grješaka je prisutnost srčanog šuma čiji stupanj, u većini slučajeva, ovisi o veličini defekta. Napredovanjem bolesti razviju se i ostali znakovi zatajivanja srca. Liječenje može biti medikamentozno ili kirurško. Lijekovima koji se koriste su blokatori beta-adrenergičkih receptora, diuretici, vazodilatatori i srčani glikozidi. Kirurška metoda koja se najčešće koristi je balonska valvuloplastika. U ovom radu obrađeni su patentni duktus arteriozus, pulmonalna stenoza, subaortalna stenoza i ventrikulski septalni defekt.

Abstract (english)

Congenital heart defects are malformations of heart structures that are present at birth. They are caused by genetic, pharmacological, toxic and other factors. The prevalence is 0.25%, and there are breed predispositions for congenital heart defects. In dogs most common congenital heart defects are patent ductus arteriosus, pulmonal stenosis and subaortic stenosis and in less cases ventricular septal defect, heart valve dysplasia, persistent right aortic arch, atrial septal defect and tetralogy of Fallot. The most important clinical feature of congenital heart defects is the presence of heart murmurs, the degree of which, in most cases, depends on the size of the defect. With the progression of the disease other signs of heart failure develop. Treatment can be medical or surgical. Medications used are beta-adrenergic blockers, diuretics, vasodilatators and cardiac glycosides. Most used surgical treatment is balloon valvuloplasty. In the present paper patent dusctus arteriosus, pulmonal stenosis, subaortic stenosis and ventricular septal defect are reviewed

• Keywords: srce; prirođene srčane grješke; pasminska predispozicija
• Keywords (english): heart; congenital heart defects; breed predisposition
• Language: croatian
• URN:NBN: urn:nbn:hr:178:566035
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-11-12 08:40:33