Pregled kazuistike tumora maternice kuja na Klinici za porodništvo i reprodukciju Veterinarskog fakulteta u desetogodišnjem razdoblju

master's thesis

• Title (english): Review of uterine tumor casuistic at the Clinic for Obstetrics and Reproduction Faculty of Veterinary Medicine, in a ten-year period
• Author: Vlatka Pižeta
• Mentor: Ivan Folnožić (mentor)
• Mentor: Silvijo Vince (mentor)
• Committee member: Branimira Špoljarić (predsjednik povjerenstva)
• Committee member: Ivan Folnožić (član povjerenstva)
• Committee member: Silvijo Vince (član povjerenstva)
• Committee member: Ivan Butković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2023-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Veterinary Clinical Sciences

Abstract

Zbog visoke zastupljenosti kirurške kastracije kuja u ranoj životnoj dobi, tumori
maternice rijetka su dijagnoza. Javljaju se u kuja srednje i starije životne dobi obično između
pete i dvanaeste godine života. Tumori maternice mogu biti benigni koji imaju dobru prognozu,
te maligni koji imaju lošiju prognozu ukoliko metastaziraju i zahvate okolne limfne čvorove. U
ovom diplomskom radu cilj je bio utvrditi karakteristike tumora s obzirom na pasminu, dob i
tjelesnu masu kuja koje su zaprimljene na Kliniku za porodništvo i reprodukciju. U istraživanju
su analizirani podaci histopatološke pretrage za ukupno 14 kuja u razdoblju od 2011. do 2021.
godine. Prosječna dob kuja na dan dijagnoze tumora maternice za križanu pasminu iznosila je
11 godina, a za čistokrvne pasmine 9 godina. U čistokrvnih pasmina zabilježeno je 23,08%
leiomioma, 23,08% fibroma te 15,38% endometrijalnih polipa. U križanih pasmina zabilježeno
je 23,08% leiomioma, 7,69% endometrijalnih polipa te 7,69% adenokarcinoma. Prosječna dob
kuje prema tipu neoplazije za leiomiom i fibrom iznosila je 9 godina, za endometrijalni polip
11 godina, a za adenokarcinom 14 godina.
Najčešći klinički znakovi koje vlasnici primijete su kronično povećanje abdomena te
vaginalni iscjedak različite boje i konzistencije. Dijagnostika tumora materrnice obuhvaća
radiografiju, ultrazvučnu pretragu, laparoskopiju i eksplorativnu laparotomiju, dok najbolji
izbor liječenja predstavlja ovariohisterektomija i histopatološka pretraga. Prognoza za većinu
tumora maternice nakon ovariohisterektomije je povoljna zbog velikog postotka benignih
tumora. Ukoliko se patohistološkom pretragom dobije nalaz malignog tumora, prognoza može
biti dobra ako nema prisutnih metastaza i lokalne infiltracije.
Rezultati ovog istraživanja potvrdili su činjenicu da su tumori maternice rijetki, da su
leiomiomi najzastupljeniji tumori te da se javljaju u kasnijoj životnoj dobi pogotovo u kuja
križane pasmine.

Abstract (english)

Due to the high incidence of surgical castration of bitches at an early age, uterine tumors
are a rare diagnosis. They appear in middle-aged and older bitches, usually between five and
twelve years of age. Uterine tumors can be benign, which have a good prognosis, and malignant,
which have a worse prognosis if they metastasize and affect the surrounding lymph nodes. In
this thesis, the goal was to determine the characteristics of tumors with regard to the breed, age
and body weight of bitches admitted to the Obstetrics and Reproduction Clinic. In the research,
the histopathological examination data for a total of 14 bitches in the period from 2011 to 2021
were analyzed. The average age of bitches on the day of uterine tumor diagnosis was 11 years
for crossbreeds, and 9 years for purebreds. In purebred breeds, 23.08% of leiomyomas, 23.08%
of fibromas and 15.38% of endometrial polyps were recorded. In crossbreds, 23.08% of
leiomyomas, 7.69% of endometrial polyps and 7.69% of adenocarcinomas were recorded. The
average age of bitches according to the type of neoplasia for leiomyoma and fibroma was 9
years, for endometrial polyp 11 years, and for adenocarcinoma 14 years.
The most common clinical signs noticed by owners are chronic abdominal enlargement
and vaginal discharge of different color and consistency. Diagnosis of uterine tumors includes
radiography, ultrasound examination, laparoscopy and exploratory laparotomy, while the best
choice of treatment is ovariohysterectomy and pathohistological examination. The prognosis
for most uterine tumors after ovariohysterectomy is favorable due to the large percentage of
benign tumors. If the pathohistological examination reveals a malignant tumor, the prognosis
can be good if there are no metastases and local infiltration present.
The results of this research confirmed the fact that uterine tumors are rare, that
leiomyomas are the most common tumors and that they occur later in life, especially in crossbreed bitches.

• Keywords: tumori maternice; benigni; maligni; metastaze; pasmina; dob; kuja
• Keywords (english): uterine tumors; benign; malignant; metastases; breed; age; bitch
• Language: croatian
• URN:NBN: urn:nbn:hr:178:405788
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-12-18 14:31:23