KOŽNI SARKOMI MAČAKA – RETROSPEKTIVNI PRIKAZ SLUČAJEVA DIJAGNOSTICIRANIH NA ZAVODU ZA VETERINARSKU PATOLOGIJU U RAZDOBLJU 2010. - 2022.

master's thesis

• Title (english): Feline skin sarcoma - a retrospective report of cases diagnosed at the Department of Veterinary Pathology in the period 2010 - 2022.
• Author: Nikolina Donkov; VIAF: 0053214350
• Mentor: Ivan-Conrado Šoštarić-Zuckermann (mentor)
• Mentor: Branka Artuković (mentor)
• Committee member: Andrea Gudan Kurilj (predsjednik povjerenstva)
• Committee member: Branka Artuković (član povjerenstva)
• Committee member: Ivan-Conrado Šoštarić-Zuckermann (član povjerenstva)
• Granter: University of Zagreb; Faculty of Veterinary Medicine; Zagreb
• Defense date and country: 2024-02, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Veterinary Medicine; Basic and Preclinical Veterinary Sciences

Abstract

Tumori su jedan od glavnih uzroka smrti domaćih ljubimaca. Tumori kože čine veliki udio u
ukupnom broju tumora u mačaka, od čega je skoro 80% maligno. Cilj ovog retrospektivnog
istraživanja je bio utvrditi pojavnost kožnih sarkoma od ukupnog broja kožnih tumora u mačaka.
Koristili smo se arhivskim podacima histopatoloških pretraga sa Zavoda za veterinarsku
patologiju, Veterinarskog fakulteta u Zagrebu u razdoblju od 1.1.2010. do 1.1.2022. godine.
Kožne tumore smo podijelili prema njihovom podrijetlu na epitelne, mezenhimalne i ostale
tumore – kategoriju u kojoj smo izdvojili tumore okruglih stanica, mastocitom, limfom,
melanom i melanocitom. Od ukupnog broja kožnih tumora (n=384), epitelnih tumora je 46,9 %,
mezenhimalnih tumora je 46,4 % i 4,8 % ostalih tumora. Utvrđeno je da je 41.6 % kožnih
sarkoma od ukupnog broja kožnih tumora. Najučestaliji kožni sarkomi mačaka u ovom
istraživanju bili su fibrosarkom, postinjekcioni sarkom, nediferencirani pleomorfni sarkom, slabo
diferencirani sarkom, hemangiosarkom, maligni tumor ovojnica perifernih živaca. Prosječna dob
oboljelih mačaka je bio 10.43 godine. Spolna predispozicija nije nađena, ali kod nekih tipova
kožnih sarkoma na temelju naših podataka uočena je blaga sklonost oboljevanja određenog
spola. Pasminsku predispoziciju nismo mogli relevantno odrediti zbog toga što je skoro 90%
mačaka iz našeg istraživanja bilo domaće pasmine.

Abstract (english)

Tumors are one of the main causes of death in domestic pets. Skin tumors make up a large
proportion of the total number of tumors in cats, almost 80% of which are malignant. The aim of
this retrospective study was to determine the occurrence of skin sarcomas out of the total number
of skin tumors in cats. We used archival data of histopathological examinations of the
Department of Veterinary Pathology of the Faculty of Veterinary Medicine in Zagreb in the
period from January 1st 2010 until January 1st 2022. We divided skin tumors according to their
origin into epithelial, mesenchymal and other tumors - a category in which we includedround
cell tumors, mast cell tumors, lymphomas, melanomas and melanocytomas. Of the total number
of skin tumors (n=384), epithelial tumors accounted for 46.9%, mesenchymal tumors for 46.4%
and other tumors for 4.8%. It was determined that 41.6% of the total number of skin tumors are
skin sarcomas. The most common cutaneous sarcomas of cats in this study were fibrosarcomas,
feline injection site sarcomas, undifferentiated pleomorphic sarcomas, poorly differentiated
sarcomas, hemangiosarcomas, malignant tumors of peripheral nerve sheaths. The average age of
the affected cats was 10.43 years. No gender predisposition was found, but in some types of skin
sarcomas, based on our data, a slight tendency to the disease of a certain gender was observed.
We could not determine the breed predisposition relevantly because almost 90% of the cats in
our study were of domestic breeds.

• Keywords: tumori kože; kožni sarkomi; mačka
• Keywords (english): skin tumors; skin sarcomas; cat
• Language: croatian
• URN:NBN: urn:nbn:hr:178:098797
• Study programme: Title: Veterinary Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-02-19 13:10:32